Publications

Human centenarian–associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids

Epigenetic and transcriptional control of adipocyte function by centenarian‑associatedSIRT6 N308K/A313S mutant

Transcriptional Control of Hepatocellular Carcinoma Cells Aggressiveness by AAV2/8-Mediated Delivery of Human Centenarian-Associated SIRT6 N308K/A313S

SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

Cell. 2019 Apr 18;177(3):622-638 

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

Cell 124, 315–329 (2006)

SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span

Cell. 2009;136:62–74

Sirtuin activators and inhibitors: Promises, achievements, and challenges

Author manuscript; available in PMC 2019 Aug 1.

Aging genes: the sirtuin story unravels

Science. 2011;334:1194–1198.

SIRT6 promotes DNA repair under stress by activating PARP1

Science 332. No.6036. June 2011: 1443-46

Epigenetics and longevity

Ageing Res Rev. 2017;40:11–19